Light Sensitivity headaches, Woman suffers from headaches caused by light
Research suggests a new pathway exists between the brain and the eye that does not produce vision but can trigger pain. The pathway begins at the back of the eye and travels through the optic nerve.

Migraine Headaches Caused by Light Sensitivity

Over 90% of migraine sufferers are sensitive to light.[1,2] During a migraine attack, sufferers are bothered by light and prefer to be in a dark room. Migraineurs are particularly sensitive to non-incandescent indoor lighting sources such as fluorescent lights, computer monitors, and gas-vapor lamps.

Migraine Sufferers Report Light Sensitivity

Although nearly all migraine sufferers report light sensitivity (photophobia) during attacks, and many report that light can trigger an attack, there are no treatments that specifically address this facet of this disease.

Ocular Migraine or “Migraine with Aura”

About a third of the migraine sufferers in the U.S. experience migraine with aura. [3] Of course, everyone is different, and symptoms vary by person and sometimes by attack. These migraines are believed to be caused by the same stimuli as a normal migraine headache, but the symptoms vary.  Ocular migraine symptoms may come in the form of enlarging blind spot, wavy or zig-zag lines surrounding the blind spot, and other vision impairments. Often these migraines are painless and will resolve without medication in 20 to 30 minutes. Learn more about ocular migraines and migraines with an aura.

migraine symptoms at the office
Light from computer monitors, fluorescent lights, and TV screens may trigger migraine attacks.

The Science behind Light Sensitivity

What Causes Light Sensitivity?  The physiological basis of light sensitivity has always been a mystery: Why is it that when one looks at a bright light, such as the sun, one feels pain? Why can light trigger a painful migraine attack? What part of the eye transforms light into a painful stimulus?

Many parts of the eye work together to transform light rays passing through your pupil into images that your brain can interpret. The retina is the very back of the eye and holds millions of cells that are sensitive to light. The retina takes the light the eye receives and converts it into electrical signals so the brain can interpret what the eye is seeing.



ocular migraine triggers and light sensitivity
Cells found in the ganglion cell layer of the retina appear to be the beginning of the light-induced “pain pathway”. These light-sensitive cells may be responsible for triggering light sensitivity and headaches.

Light Sensitivity Can Produce Pain

However, research performed in 2010 by Harvard and University of Utah scientists suggest that an additional pathway between the eye and brain exists that does not produce images – it may produce pain. [4] In the early 1990’s, a unique subset of cells in the retina were found to be intrinsically sensitive to light.

It is likely that the pain pathway begins with these intrinsically light sensitive cells and can transform light absorbed by the eye into a painful stimulus. This pain pathway is completely separate from and independent of the image-forming pathway. [5] Because it is a separate pathway, even some profoundly blind patients can be profoundly light sensitive. [6]



1 Source: Evans RW, Seifert T, Kailasam J, Mathew NT. The use of questions to determine the presence of photophobia and phonophobia during migraine. Headache 2008;48:395-7.
2 Source: Main A, Dowson A, Gross M. Photophobia and phonophobia in migraineurs between attacks. Headache. 1997. 37:492-5.
3 Source: Cortical spreading depression—Migraine: a complex genetic disorder; Lancet Neurology, Wessman, 2007
4 Source: Noseda R, Kainz V, Jakubowski M, Gooley JJ, Saper CB, Digre K, Burstein R. A neural mechanism for exacerbation of headache by light. Nat Neurosci. 2010. 13:239-45.
5 Source: Güler AD, Ecker JL, Lall GS, et al. Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision. Nature. 2008. 453:102-5.
6 Source: Amini A, Digre K, Couldwell WT. Photophobia in a blind patient: An alternate visual pathway. Case report. J Neurosurg. 2006. 105:765-8.

3 thoughts on “Light Sensitivity Triggers Migraines

  1. Anon says:

    Has anyone had a migraine triggered by the bright light of an ophthalmic exam? This occurred to me recently; now l fear further ophthalmic exam, but may need it due to eye pain.

  2. kay warner says:

    Yes, I had a very bad reaction to High Resolution Tomography in the opthalmology clinic. The bright light caused actual pain, and afterwards I had one of the worst migraine attacks I’ve ever experienced. A warning not to use it was put on my clinic notes and I was also advised to let my GP know. The usual eye examinations don’t cause a problem for me.

Leave a Reply

Your email address will not be published. Required fields are marked *